Skin: AJCC8 melanoma T staging
Free question published 21 September 2026
A 49-year-old woman has an excision biopsy of a changing mole on her shoulder. Histopathology reports a cutaneous melanoma with a Breslow thickness of 0.6 mm, no ulceration, and a mitotic rate of 4 per mm2. There is no clinical evidence of nodal or distant disease. Which T category should be assigned to this primary tumour?
- AT1a
- BTis (in situ)
- CT1b
- DT2a
- ET2b
Why A is correct
Under AJCC 8th edition, T1a is a non-ulcerated melanoma less than 0.8 mm thick. Crucially, mitotic rate is no longer used to subcategorise T1 melanomas, so a high mitotic rate does not upstage a 0.6 mm non-ulcerated tumour to T1b. This lesion is therefore T1a.
And why the others are not
- BIncorrect: an invasive melanoma with a measurable Breslow thickness is not in situ (Tis).
- CIncorrect: T1b is 0.8-1.0 mm (any ulceration status) or under 0.8 mm with ulceration; this lesion is under 0.8 mm and non-ulcerated, and mitotic rate does not apply.
- DIncorrect: T2 applies to tumours greater than 1.0 mm up to 2.0 mm, which this 0.6 mm lesion is not.
- EIncorrect: T2b requires a 1.0-2.0 mm ulcerated tumour, neither of which applies here.
Source AJCC 8th edition melanoma staging - key changes — Gershenwald JE, Scolyer RA, Hess KR, et al. Melanoma staging: Evidence-based changes in the American Joint Committee on Cancer eighth edition cancer staging manual. CA Cancer J Clin. 2017;67(6):472-492.
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